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Importantly, no serious AEs were observed, and only one patient (0.8% of the safety cohort) discontinued treatment owing to mild injection site pain

The most commonly reported side effects were gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, which were generally mild to moderate and occurred mainly during dose escalation

Metformin remains a common first-line option for many adults, although not everyone can use it

Cellular schwannoma: a variety of schwannoma sometimes mistaken for a malignant tumor

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