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Endurance performance and energy metabolism during exercise in mice with a muscle-specific defect in the control of branched-chain amino acid catabolism

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Several sex effects were also observed throughout these studies, where despite higher levels of total plasma acylcarnitines in females compared to males, in aging females, there was a significant decrease in total acylcarnitines which was not seen in aging males, indicating that aging may impact female peripheral lipid bioenergetics more than males

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J Leukoc Biol 52:135142 Blomberg OS, Spagnuolo L, Garner H, Voorwerk L, Isaeva OI, van Dyk E, Bakker N, Chalabi M, Klaver C, Duijst M et al (2023) IL-5-producing CD4(+) T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer