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B12 Side Effects in Elderly: Safety Guide for Older Adults Vitamin B12 supplementation is commonly prescribed for elderly patients, as deficiency becomes increasingly prevalent with age due to reduced gastric acid production, pernicious anaemia, and medication interactions

Older adults are also at a higher risk of B12 deficiency due to decreased stomach acid levels, which are needed to separate B12 from protein in the diet for absorption

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B12 is not a cure for clinical depression or anxiety, so persistent mood symptoms should be evaluated by a provider