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In rodent models, it has been reported to protect against various gastrointestinal insultsulcers, NSAIDinduced lesions, ischemia/reperfusion injuryby promoting angiogenesis, upregulating growth factors, and modulating nitric oxide pathways

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To extend this data, investigation of the effects of formononetin on IgE production by PBMCs of food-allergic patients in vitro was performed [121]