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14,15 Because of the results of these landmark clinical trials, evidence-based treatment guidelines now recommend the GLP-1/GIP agonists as an important second-line treatment for uncomplicated type 2 diabetics who fail to meet hemoglobin A1c targets on popular first-line agents such as metformin

These studies have strengthened the evidence that IGF-1 can directly contribute to cancer development

A low CoQ10 level increases inflammatory signaling and is linked to poor cardiovascular health and outcomes, and CoQ10 supplements have a potential role in preventing and as an adjuvant to treating cardiovascular disease and associated metabolic conditions

Maes 2009