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Because glutamate released during neurotransmission is recycled via glutamine in glial cells, glutamine may index glutamate neurotransmission

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The lipid vesicles shield the glutathione from digestive enzymes, facilitating its uptake in the intestines

Given that the majority of ARG is decomposed by the liver (arginase), this inter-organ cycle of ARG-L-citrulline-ARG can safeguard ARG from excessive degradation by the liver