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2017;255(11):2255-2261 Rougier MB, Delyfer MN, Korobelnik JF

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75 While standard melatonin supplements rapidly increase blood melatonin levels and can shorten the time needed to fall asleep, newer extended-release formulations have been found to sustain higher melatonin levels through the night in healthy individuals and hold promise for their potential to better maintain sleep through the night