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For example, a single oral administration of the sheep-derived phage CEV1 was reported to reduce the abundance of Escherichia coli O157:H7 in the ovine intestine by approximately two log units within 2 days 200

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An in vitro study revealed that AGEs binding to RAGE on macrophages and microglia promote oxidative stress by activating NF-KB, and MAPK, c-Jun N-terminal kinase (JNK), and p21RAS signaling pathways (197)