What should I expect in the first week
The SURMOUNT-5 trial (published in NEJM, 2025) demonstrated mean weight loss of 20.2% with tirzepatide versus 13.7% with semaglutide over 72 weeks in adults with obesity but without diabetes [10]
Similar content being viewed by others Introduction Parkinsons disease (PD) is a chronically progressive disease, that most commonly manifests between the fifth and seventh decade with resting tremor on one or both sides, bradykinesia, rigidity and abnormal postural reflexes 1
For someone with metabolic syndrome who jumps on a GLP-1 and drinks heavily every weekend, thats a different risk profile than someone with well-controlled diabetes, normal lipids, and no alcohol use, Perez said
But until Clarkson confirms it herself, those claims remain unverified