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La causa puede ser una variedad de factores

The principal gastrointestinal metabolites of glutamine (glutamate, proline, ornithine, citrulline and ammonium) [21] were less effective or inactive as secretagogues, suggesting that metabolism via these pathways is not responsible for the amplifying action of glutamine

MT-1 can trigger mild nausea and appetite suppression in 1520% of subjects during initial dosing, typically resolving within 48 hours as melanocortin receptors downregulate

Glutathione helps protect the skin from oxidative stress, reduces hyperpigmentation, and promotes a more even skin tone

Liver Int 2011, 31 (9), 13151324.10.1111/j.1478-3231.2011.02602.x [DOI] [PubMed] 120.M