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The decrease in astrocyte remodeling in OHT eyes treated with SEM is consistent with a previous study of experimental glaucoma where systemic administration of the GLP-1RA NLY01 decreased reactive astrocyte transformation [9]

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In human microvascular endothelial cells as well as human umbilical vein endothelial cells, Eltzschig and colleagues showed that hypoxia increased DPP4 mRNA and protein level (175), whereas another study by Shigeta et al

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