Meta-analysis of renal outcomes shows GLP-1 RAs reduce renal events by 15%, primarily through prevention of albuminuria, and mortality by 11%, with no difference between agents
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Nevertheless, vulvar melanoma may occur in the young, and nevi are certainly encountered in older women
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A qualified healthcare provider must evaluate contraindications, prior GLP-1 tolerance, renal and thyroid status, and personal or family history of medullary thyroid cancer