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Klonoff, MD, medical director of the Diabetes Research Institute at Mills-Peninsula Medical Center in San Mateo, California, noted that the findings of the Hathaway study, based on a single tertiary care university eye clinic, might not pertain to the general population. To assess the risk of NAION in patients prescribed semaglutide for diabetes or obesity, he performed a series of real-world analyses based on the electronic health record and claim dataset of Atropos Health, comprising 66 million people nationally

If youre considering it, have an honest conversation with a responsible prescriber to define expectations and weed out potential hazards

Understanding these secondary effects helps distinguish normal physiological adaptations from symptoms requiring medical attention

Is this an attempt to pivot regulators from hard localization mandates toward soft operational guidelines

Many GLP-1 users need 2,000-5,000 IU of vitamin D daily to maintain adequate levels, and standard multivitamin doses of 400-800 IU may not be sufficient