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An in vitro study (Teixeira and Rumjanek, 2014) showed that human monocytes treated with ouabain at a concentration of 100 nM produced heightened levels of early markers of monocyte activation: IL-1, TNF-, IL-10, vascular endothelial growth factor (VEGF), surface monocyte activation markers such as CD69, a transmembrane type II C-lectin receptor, and HLA-DR (Human Leukocyte AntigenDR isotype) (Ziegler et al., 1994)

Long term use of beinaglutide, a recombinant human GLP-1(7-36) acid, was demonstrated to reduce the body weight and improve steatosis (194)

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These treatments include mB12/LDFA, BH4 and HDFA

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