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It downregulates p53 and upregulates the expression of SLC7A11 and GPX4, suggesting that it improves cartilage degradation in osteoarthritis by inhibiting ferroptosis through the regulation of the p53 signaling pathway, indicating its potential therapeutic effect in osteoarthritis [166]

If you take blood thinner medications, talk to your healthcare provider or pharmacist before adding these or other dietary supplements

This dosing schedule helps maintain more stable blood levels of berberine, as it is rapidly metabolised

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Cancers 6 , 17691792 (2014)