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ArodaVRBauerRChristiansenEHaluzkMKallenbachKMontanyaEet al

More than half of patients (53%) stop using GLP-1s within the first year, according to a December 2025 Sermo survey of physicians

Future direction The evolution of GLP-1RAs is increasingly shifting toward oral formulations, aiming to enhance patient adherence by eliminating the need for injections and addressing the logistical complexities associated with traditional peptide therapies [72, 73]

This holistic approach to my health seems to have mitigated the common side effects associated with tirzepatide, making the initial phase of my journey much smoother than anticipated

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