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The peak heart rate effect is temporary, not permanent

Nature (2012) 486:20714

The inclusion criteria were (i) studies involving dietary or food polyphenols and their health outcomes, (ii) studies reported on bioavailability and metabolism of dietary polyphenols, (iii) studies performed in gut-microbiota-aided dietary polyphenol metabolites and their effects in vitro or in vivo models, (iv) interaction between dietary polyphenols and gut microbiotas, and (v) studies published from 2011 to 2025 (15 years, both years included)

Foa PP, Galansino G, Pozza G

Now, the growing buzz around the use of GLP-1 medications like Ozempic to treat alcohol use disorder finally has new clinical study results that support this theory