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Ethics declarations Conflict of interest Mette JF Nielsen, Helene H Hansen Duus, Katrine Kirkeby, Britt W Lauenborg, Benjamin Low and Louise Witten are employees and stockholders of Novo Nordisk A/S

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In a 2013 study by Korenevsky et al., the researchers administered a combination of melatonin and epithalon to female rats exposed to suboptimal environmental factors, such as light pollution, finding that the combined therapy rectified various impairments of the hypothalamic-pituitary-gonadal axis [13]

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