It's a hormone produced in your gut after you eat, and it plays three critical roles in how your body processes a meal (Muller et al., Molecular Metabolism, 2019): It tells your brain you're full
Delayed gastric emptying They decrease gastric motility and prolong the feeling of fullness leading to reduced food intake
Date: April 23, 2026 Source: Digestive Disease Week Summary: A new minimally invasive procedure may help people keep weight off after stopping popular drugs like Ozempic and semaglutidesomething most patients struggle with
In the brain, it activates GLP-1 receptors in the hypothalamus reducing hunger signals and increasing satiety, so that you feel full sooner and satisfied longer after eating, naturally reducing caloric intake without the psychological struggle of rigid dieting
Immunohistochemical and Histochemical Analysis GFAP immunostaining was performed to assess glial activity and astrocyte response in the hippocampus ( Fig