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Some notice a subtle improvement in energy levels

CSD has been demonstrated to activate the trigeminovascular system (TVS) both centrally and peripherally by exposing the dura to inflammatory molecules, indicating that susceptibility to CSD may contribute to the initiation of migraine attacks (26, 27)

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After 60 weeks, off-medication scores on MDS-UPDRS Part III improved by 1.0 point (95% CI: -2.6 to 0.7) in the exenatide group, whereas the placebo group experienced a decline of 2.1 points (95% CI: -0.6 to 4.8)