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CNS Drugs 39 , 12011220 (2025)

These are GLP-1, GIP and glucagon receptors

4) Integrate multi-disciplinary approaches for clinical translation: Combine artificial intelligence (AI)-driven drug discovery (e.g., machine learning models to predict ferroptosis modulator efficacy using multi-omics data) with network pharmacology to identify synergistic drug combinations (e.g., ferroptosis inhibitors + anti-fibrotic agents)

Finally, a recent network meta-analysis that compared cognitive outcomes with various antidiabetic agents in patients with type 2 diabetes observed that GLP-1RAs ranked second after sodium-glucose cotransporter-2 inhibitors for reducing dementia risk

Exercise Regularly Physical activity has been shown to enhance antioxidant levels, including glutathione