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NO is synthesized by three types of NO synthase (NOS): endothelial NOS (eNOS), neuronal NOS (nNOS), and inducible NOS (65)

Precisely regulated ROS bursts activate defense and acclimation pathways, whereas prolonged or uncontrolled accumulation disrupts cellular integrity, leading to lipid peroxidation, protein oxidation, and genomic instability

Additionally, lifestyle factors such as poor diet, stress, and lack of sleep can also contribute to the risk of developing a yeast infection

Phentolamine is an alpha-blocker that further enhances blood flow by blocking certain receptors in the smooth muscle cells of the blood vessels

lactis strain HN019, 10 billion CFUs of L