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Endocrinology 142(11):49694975 Freude S, Leeser U, Mller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Khler C, Schrder H, Krone W (2008) IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination