Compared with traditional small-molecule drugs, GLP-1 peptides are structurally more complex and can exist in multiple molecular forms
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An important feature of the technology is that, depending on the physicochemical properties of the nanoparticles, the drug molecules can be taken up preferentially by the blood circulation (smaller molecules) or first via lymphatic absorption (larger molecules)
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Furthermore, the intestinal mucosa of rats that received APO + MTX revealed weak positive immunological staining for cleaved caspase-3 (Mansoury et al