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The clinical program and Phase 2b failure Phase 1 and 2a trials were successful , the peptide was safe, without significant side effects, and showed a mild lipolytic signal

Robust, head-to-head studies are needed to clarify the therapeutic potential and mechanistic diversity of these compounds before their clinical application in DOR management can be meaningfully assessed

Although oxidative stress and necrosis were reported to be related to herbal products toxicities, the underlying mechanism is largely unknown (Stickel and Shouval, 2015)

The insight that changes the research agenda: an aged immune system does not just decline, it actively accelerates decline elsewhere.

Diabetes 2 , 217220 (2011)