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10.1016/j.phymed.2024.155356 117 ShiW.ZhangW.WangJ

Zhang T, Hu L, Tang JF, Xu H, Tian K, Wu MN, Huang SY, Du YM, Zhou P, Lu RJ, He S, Xu JM, Si JJ, Li J, Chen DL, Ran JH (2021b) Metformin inhibits the urea cycle and reduces putrescine generation in colorectal cancer cell lines

This pathway has been explored for its role in reducing visceral fat

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Selank specifically has shown anxiolytic effects through GABA and serotonin modulation without the dependence risk of benzodiazepines or the side effect profile of SSRIs