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While the drug appeared to show higher rates of certain gastrointestinal side effects, such as nausea and diarrhea, especially at the highest dose, they were generally consistent with a previous Phase 3 trial of retatrutide in patients with obesity and a type of knee arthritis pain

Needless to say, I was excited to see how Metabolic Daily could move the needle on my gastro-imbalances

UK dietary reference values recommend approximately 0.75g of protein per kilogram of body weight daily, though during weight loss, higher intakes (1.0-1.2g/kg/day) may help preserve lean muscle mass

These medications carry a boxed warning about thyroid C-cell tumors observed in rodent studies and are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

9 Retatrutide is also part of a wider pipeline of new weight-loss medications expected over the next 2-3 years