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Interestingly, however, common responses to GLP1/E were observed in both PCOS models, with upregulation of hypothalamic pathways involved in autophagy and vesicle-mediated transport, and downregulation of pathways primarily related to the immune system

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The development of recombinant DNA technologies, synthetic biology and metabolic engineering, alongside biosafety and high production yields, has enhanced the value of certain yeasts as cell factories for production [2]

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