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Adjust for GI days: if nausea is high, use smaller meals, smaller protein shakes, and mix creatine into whatever you can keep down

If you're particularly anxious, let your provider know

Other common digestive side effects include: Vomiting: Often occurs alongside nausea, especially when starting treatment Diarrhea: Usually mild and temporary Constipation: Can occur as your digestive system adjusts Stomach pain: Typically mild and manageable Loss of appetite: While this contributes to weight loss, it can be concerning for some patients These digestive effects happen because GLP-1 slows how quickly food moves through your stomach

PMID: 27738444

Accessed 29-01-2025 Pawlak M, Lefebvre P, Staels B