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Evidence supports several interventions: Cognitive behavioral therapy (CBT) : Randomized controlled trials demonstrate that CBT specifically designed for menopausal symptoms reduces hot flash-related distress and improves quality of life, even when frequency remains unchanged [35] [36] Clinical hypnosis : Studies show significant reductions in hot flash frequency and interference with daily activities [40] Weight management : Obesity correlates with increased hot flash severity

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It belongs to a class of drugs known as sympathomimetic amines, meaning it mimics adrenaline-like signals in the body

Another theory places the onus on an endometrial defect based on reports of decreased expression for several biomarkers of implantation