semaglutide water intake How to Stay Hydrated While Taking GLP-1s Does Ozempic Make You Thirsty?

Last reviewed: June 21, 2026 Last updated: June 21, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Bill would learn that the hard way

Research which looked at the genetics of nearly 28,000 people taking a GLP-1 drug also identified genetic issues in another set of receptor genes called GLP-1R and GIPR

Twelve hours later, you realized it never went back in the fridge

Side effects that cause dehydration and kidney problems: Ozempic can cause side effects such as vomiting and diarrhea, which may lead to dehydration