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doi: 10.1007/s11154-020-09609-x, 98

Published in the New England Journal of Medicine in 2025, this Phase 3 study enrolled 610 Chinese adults with obesity or overweight accompanied by at least one weight-related comorbidity

These data combined with the effect of GLP-1R in chronic pain suggest that activation of GLP-1R may also alleviate CM

Levels of RBC vesicle contamination in the purified platelet fraction were measured by determining the levels of glycophorin A (GPA) positive fragments using an anti-human GPA antibody (BD Bioscience, Pharmagen, San Diago, CA) and analysis by flow cytometry

These findings suggest potential relevance not just for longevity, but also for regenerative medicine and age-related tissue repair