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Drug Design, Development and Therapy, 14 , 53675374
It achieves this by modulating MMPs and by attracting immune cells and endothelial cells to injury sites
Kim et al ., Reference Kim, Ahn, Kim, Bae, Kwon, Kang, Yang, Sohn and Kong2016
At the same time, liver inflammation, intestinal flora displacement and concurrent infection caused by cirrhosis lead to the release of a large number of inflammatory factors and endotoxemia, causing renal microcirculation dysfunction, which can induce renal function injury (Rad et al., 2024)
502,503 It also contributes to inhibiting inflammatory responses by reducing mtROS level, suppressing the NLRP3 inflammasome, and promoting M2 microglia polarization
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