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3.5.2 GLP-1 modulation within reward networks and downregulation of motivation The reward network can be conceptualised as a distributed circuit involving the ACC, OFC, ventral striatum, ventral pallidum, and midbrain dopaminergic systems, with additional modulation by structures such as the amygdala and hippocampus (54, 55)

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However, it is crucial to consider that SLC7A11 expression in HSCs is significantly higher than in hepatocytes under acute liver injury conditions, making HSCs more sensitive to these inhibitors

A neurobiological perspective on early human deprivation