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Their effectiveness depends on consistent use, medical supervision, and lifestyle alignment

In clinical trials, patients lost an average of 2% of their body weight per month for the first six months, then 1% per month for the next six months, totaling a 16% weight loss by the end of the first year

I was pretty sure I had read that migraines could be related to low B12, but can't remember the source for that - here is an article about a study which found a greater serum B12 hugely decreased the chance of migraine: neurologyadvisor.com/adviso

10.1111/j.1469-8137.2006.01643.x 114 SairamK.RaoK

The gradual 30-day dose escalation schedule is specifically designed to make these side effects easier to tolerate