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Gutbrain axis and gastrointestinal cytoprotection Given its gastric origin, a large body of preclinical work has investigated BPC-157's effects on gastrointestinal mucosal integrity, including in models of NSAID-induced gastric damage and experimental colitis

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Besides the morphine-antagonist naloxone, the central dopamine antagonist haloperidol has also been tested, presenting this peptide's close interaction with the dopamine system (11, 15-17, 19)

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