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The decision for the blend over a single substance is ultimately a question of the research question: synergy and pulse logic on the one hand, defined single-substance kinetics on the other

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[5] It has been hypothesized to act through GH-mediated pathways on the osteoblasts (bone-forming cells), possibly leading to increased proliferation, development, and differentiation of the osteoblasts

However, periodic breaks may help maintain receptor sensitivity