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3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: A randomised, double-blind trial

Our study highlights several biological pathways by which GLP1 drugs may influence Alzheimers, including reducing inflammation, improving insulin signalling in the brain, and altering enzymes involved in the production of amyloidbeta

DPP-4i = dipeptidyl peptidase-4 inhibitor

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1 Thus, numerous studies have used biotechnology to extend the half-life of GLP-1 RAs, with strategies including amino acid sequence substitution, fatty acid conjugation with a linker, fusion of albumin or the IgG fragment crystallizable (Fc) region (Figure 1)