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Comment: A few commenters expressed concern regarding the reporting and implementation burden of the proposal by requiring the 2025 version of the High Priority Practices SAFER Guide beginning with the CY 2026 performance period/2028 MIPS payment year, particularly for MIPS eligible clinicians with limited resources

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Combination of high-dose parenteral ascorbate (Vitamin C) and alpha-lipoic acid failed to enhance tumor-inhibitory effect but increased toxicity in preclinical cancer models