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Multi-target strategies for the improved treatment of depressive States: conceptual foundations and neuronal substrates, drug discovery and therapeutic application

Mais les tudes menes jusquici sur leffet dune supplmentation en L-carnitine -notamment dactyl-L-carnitine- ont donn des rsultats contradictoires (3,4) certaines trouvant un effet bnfique, dautres non- et mme les tudes les plus rcentes ne sont pas parvenues une conclusion claire (5)

Zhu S, Viejo-Borbolla A

Compared to nondiabetic patients, myocardial dysfunction incidence was much higher in patients with diabetes, which was due to cardiac metabolic disturbance characterized by high FFA and reduced glucose utilization (Herlitz et al., 1988)

Therefore, this review discusses aging-associated visceral adiposity mechanisms, focusing on the adipose turnover rate and inflammatory microenvironment