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All statistical analyses were performed using R statistical software version 3.4.1 (package rms, ggplot, visreg, and mass) or Statistical Package of Social Sciences version 20.0 for Windows (IBM Corp., Armonk, NY)

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This method has been shown to reduce uncomfortable symptoms, and physicians have the requisite knowledge and experience to guide the patient through this process. Ultimately, whether you or your loved one are considering a scheduled medication holiday, tapering medication use, or switching to a different medication altogether, a conversation should be had with the prescribing healthcare provider, where team-based, informed decision-making is used to determine what is best for each person