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doi: 10.1186/s13048-025-01734-y

Its supplied in a prefilled dosing pen which should be injected subcutaneously once every week, without being subject to the timing of meals

Following this observation, and based on the hypothesis that GLP-1 can activate PKC, as demonstrated in pancreatic -cells [50] or during an exendin-4 brain infusion, we have demonstrated that overall PKC activity is increased in the hypothalamus of diabetic HFD-fed mice in the fed state and during hyperinsulinemic euglycemic clamps [110]

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