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Liver : Safe when prescribed, but monitor in patients with severe liver disease

Tirzepatide is the symbol of the status quo, while retatrutide is the symbol of the near future

Who is Tirzepatide Best For

Sometimes, the most important pharmacovigilance insights emerge not from clinical trials, but from real-world adverse event reporting

In a study that included 321 female volunteers with and without signs of PCOS, higher morning melatonin levels were associated with expression of a higher number of PCOS-related features (hyperandrogenism, few or no periods, and cystic ovaries), suggesting PCOS may be associated with disrupted circadian signaling