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In exploratory research, retatrutide represents the most ambitious incretin agent currently available

J Clin Endocr Metab 2010;95:3347-51

The AOD 9604 helps manage the output by signaling the body to burn through stored fat more efficiently

Altered liver gene expression in CCl4-cirrhotic rats is partially normalized by insulin-like growth factor-I

Both medications can lead to loss of lean muscle mass alongside fat, and adequate protein (0.7 to 1.0 grams per pound of body weight daily) helps preserve muscle