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Endocrinology 140 , 29242927 (1999)

John Horneff, an associate professor of orthopedic surgery at the University of Pennsylvania and the lead author of the study, said he began looking into the issue after some patients appeared to develop serious tendon tears after relatively minor injuries

You may recognize brand names such as Ozempic, Wegovy, Mounjaro and Zepbound

They have obesity, but it's preclinical obesity as a disease