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Gut Barrier Disruption: NSAIDs are known to impact gut health by increasing intestinal permeability, sometimes referred to as "leaky gut." This can trigger systemic inflammation, which further contributes to oxidative stress

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While glutathione is naturally produced by the body, injectable treatments involve introducing additional amounts externally, which is why professional guidance is recommended

Passive smoking exposure was also associated with an increased risk of AMD in non-smokers (Khan 2006)