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Gastrointestinal AEs, such as nausea and vomiting, as well as diarrhea and constipation, are relatively more common with dual and triple incretins

Rinaldi-Carmona M, Barth F, Millan J, Derocq JM, Casellas P, Congy C, et al

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Durability and relapse: less rebound with surgery One key limitation of GLP-1 therapy is that its benefits often depend on ongoing use