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J Cell Physiol 199:7788 Gomes-Porras M, Cardenas-Salas J, Alvarez-Escola C (2020) Somatostatin analogs in clinical practice: a review

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Irreversible aggregates do not revert back to their monomeric forms and can be caused by the rearrangement of disulfide bonds or the formation of new structures due to hydrophobic association

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