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In vivo, LA exists as free and protein-bound (predominant form) and is formed by the substitution of sulfur groups for hydrogen at positions 6 and 8 of octane groups [26]

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Some specific bacterial strains like Lactobacillus acidophilus have been shown to promote GLP-1 secretion, and their depletion in Hashimoto's patients may partially explain why weight management becomes so challenging even before considering thyroid hormone levels

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