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MuskietMHATonneijckLSmitsMMvan BaarMJBKramerMHHHoornEJet al

This extended absorption phase means subcutaneous dosing maintains detectable serum levels for 68 hours compared to 34 hours for IV administration at equivalent doses

124 However, an analysis of 62 SRL-resistant acromegalic patients indicated better IGF1 normalization with pegvisomant monotherapy compared to combined pegvisomant/SRL treatment

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